Nasal spray combination of rifampicin, resveratrol could cure dementia - Study Finds

( December 31, 2021; Study Finds )

Description: The potentially groundbreaking treatment combines an antibiotic called rifampicin with resveratrol -- an antioxidant found in plants.

Previous studies by the team found that rifampicin could remove amyloid beta and tau from the brains of mice. However, the drug also has a link to side-effects, including liver damage. Luckily, resveratrol boosts the functioning of the organ. It’s a naturally occurring ingredient in wine, fruit, nuts, and chocolate — and manufacturers sell it as a food supplement.

“To combat the negative side effects of the existing drug rifampicin, we thought of combining it with the hepatoprotective effects of resveratrol,” Prof. Tomiyama says.

With our aging demographics, the problems of autism and dementia become increasingly important all around the globe. The possible advance described here has yielded promising results in animal testing and is now being queued up for human trials.

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